Effect of Capparis spinosa L. on cognitive impairment induced by D-galactosein mice via inhibition of oxidative stress

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Effect of Capparis spinosa L. on cognitive impairment induced by D-galactose in mice via inhibition of oxidative stress.

BACKGROUND/AIM To determine the phenolic acid levels and DNA damage protection potential of Capparis spinosa L. seed extract and to investigate the effect of the extract on cognitive impairment and oxidative stress in an Alzheimer disease mice model. MATERIALS AND METHODS Thirty BALB/c mice divided into 5 groups (control, D-galactose, D-galactose + C. spinosa 50, D-galactose + C. spinosa 100,...

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Effect of Capparis spinosa Linn. extract on lipopolysaccharide-induced cognitive impairment in rats.

Cognitive disorders in mankind are not uncommon. Apart from neurodegenerative diseases such as Alzheimer's (AD), various stresses also affect cognitive functions. Plants are known to be potential source of compounds that ameliorate several diseases including cognitive impairment. Here, we evaluated effect of aqueous extract of caper (Capparis spinosa) buds on lipopolysaccharide-induced cognitiv...

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Capparis spinosa L. aqueous extract evokes antidiabetic effect in streptozotocin-induced diabetic mice

OBJECTIVE As the aqueous extract of Capparis spinosa (CS) possess antidiabetic effect, he present study aims to reveal the possible mechanism of action of CS in diabetic mice. MATERIALS AND METHODS Both single and repeated oral administrations of aqueous extract of CS were performed in multi-low dose streptozotocin-induced (MLDS) diabetic mice. Euglycemic hyperinsulinemic clamp was used in as...

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the effect of aqueous extract of garlic on formalin-induced pain in male rats

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Capparis spinosa L. aqueous extract evokes antidiabetic effect in streptozotocin-induced diabetic mice

Objective: As the aqueous extract of Capparis spinosa (CS) possess antidiabetic effect, he present study aims to reveal the possible  mechanism of action of CS in diabetic mice.Materials and Methods: Both single and repeated oral administrations of aqueous extract of CS were performed in multi-low dose streptozotocin-induced (MLDS) diabetic mice. Euglycemic hyperinsulinemic clamp was used in as...

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ژورنال

عنوان ژورنال: TURKISH JOURNAL OF MEDICAL SCIENCES

سال: 2015

ISSN: 1300-0144,1303-6165

DOI: 10.3906/sag-1405-95